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KMID : 0043320060290060431
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Archives of Pharmacal Research
2006 Volume.29 No. 6 p.431 ~ p.458
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Antiretroviral Therapy 2006: Pharmacology, Applications, and Special Situations
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Samuel Rafik
Bettiker Robert
Suh Byung-Se
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Abstract
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As we approach the completion of the first 25 years of the human immunodeficiency virus (HIV) epidemic, there have been dramatic improvements in the care of patients with HIV infection. These have prolonged life and decreased morbidity. There are twenty currently available antiretrovirals approved in the United States for the treatment of this infection. The medications, including their pharmacokinetic properties, side effects, and dosing are reviewed. In addition, the current approach to the use of these medicines is discussed. We have included a section addressing common comorbid conditions including hepatitis B and C along with tuberculosis.
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KEYWORD
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HIV, Antiretroviral therapy, Viral load, CD4 count, Nucleoside reverse transcriptase inhibitors, Non nucleoside reverse transcriptase inhibitors, Protease inhibitors
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